High risk allele frequency (A) : (0 - 1) Prevalence : (0.0001 - 0.9999) Genotype relative risk Aa : ( >1 ) Genotype relative risk AA : ( >1 ) D-prime : (0 - 1) Marker allele frequency (B) : (0 - 1) Number of trios : (0 - 10000000) User-defined type I error rate : (0.00000001 - 0.5) User-defined power: determine N : (0 - 1) (1 - type II error rate)